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Derepression of Cancer/Testis Antigens in cancer is associated with distinct patterns of DNA Hypomethylation

BACKGROUND: The Cancer/Testis Antigens (CTAs) are a heterogeneous group of proteins whose expression is typically restricted to the testis. However, they are aberrantly expressed in most cancers that have been examined to date. Broadly speaking, the CTAs can be divided into two groups: the CTX antig...

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Hlavní autoři: Kim, Robert, Kulkarni, Prakash, Hannenhalli, Sridhar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618251/
https://ncbi.nlm.nih.gov/pubmed/23522060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-144
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