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Rule-based multi-scale simulation for drug effect pathway analysis

BACKGROUND: Biological systems are robust and complex to maintain stable phenotypes under various conditions. In these systems, drugs reported the limited efficacy and unexpected side-effects. To remedy this situation, many pharmaceutical laboratories have begun to research combination drugs and som...

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Autors principals: Hwang, Woochang, Hwang, Yongdeuk, Lee, Sunjae, Lee, Doheon
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618249/
https://ncbi.nlm.nih.gov/pubmed/23566173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6947-13-S1-S4
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