Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality

Human mesenchymal stem/stromal cells (hMSC) are increasingly used in advanced cellular therapies. The clinical use of hMSCs demands sequential cell expansions. As it is well established that membrane glycerophospholipids (GPL) provide precursors for signaling lipids that modulate cellular functions,...

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Detalhes bibliográficos
Main Authors: Kilpinen, Lotta, Tigistu-Sahle, Feven, Oja, Sofia, Greco, Dario, Parmar, Amarjit, Saavalainen, Päivi, Nikkilä, Janne, Korhonen, Matti, Lehenkari, Petri, Käkelä, Reijo, Laitinen, Saara
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617938/
https://ncbi.nlm.nih.gov/pubmed/23271708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M030650
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