Defective posttranslational processing activates the tyrosine kinase encoded by the MET proto-oncogene (hepatocyte growth factor receptor).

The MET proto-oncogene encodes a 190-kDa disulfide-linked heterodimeric receptor (p190 alpha beta) whose tyrosine kinase activity is triggered by the hepatocyte growth factor. The mature receptor is made of two subunits: an alpha chain of 50 kDa and a beta chain of 145 kDa, arising from proteolytic...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Mondino, A, Giordano, S, Comoglio, P M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.12.6084-6092.1991
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