Lactoferrin- Endothelin-1 Axis Contributes to the Development and Invasiveness of Triple Negative Breast Cancer Phenotypes

Triple-negative breast cancer (TNBC) is characterized by the lack of expression of ERα, PR and HER-2 receptors and the pathway(s) responsible for this downregulation and thus aggressiveness, remains unknown. Here we discovered that lactoferrin (Lf) efficiently downregulates the levels of ERα, PR and...

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Main Authors: Ha, Ngoc-Han, Nair, Vasudha, Reddy, Divijendra Natha Sirigiri, Mudvari, Prakriti, Ohshiro, Kazufumi, Ghanta, Krishna Sumanth, Pakala, Suresh B., Li, Da-Qiang, Costa, Luis, Lipton, Allan, Badwe, Rajendra A., Fuqua, Suzanne, Wallon, Margaretha, Prendergast, George C., Kumar, Rakesh
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617573/
https://ncbi.nlm.nih.gov/pubmed/22006997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1143
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