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First Experience with Clinical-Grade [(18)F]FPP (RGD)(2): An Automated Multi-step Radiosynthesis for Clinical PET Studies

PURPOSE: A reliable and routine process to introduce a new (18)F-labeled dimeric RGD-peptide tracer ([(18)F]FPP(RGD)(2)) for noninvasive imaging of α(v)β(3) expression in tumors needed to be developed so the tracer could be evaluated for the first time in man. Clinical-grade [(18)F]FPP (RGD)(2) was...

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Main Authors: Chin, Frederick T., Shen, Bin, Liu, Shuanglong, Berganos, Rhona A., Chang, Edwin, Mittra, Erik, Chen, Xiaoyuan, Gambhir, Sanjiv S.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617483/
https://ncbi.nlm.nih.gov/pubmed/21400112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0477-3
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