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A Tunable, Modular Approach to Fluorescent Protease-Activated Reporters

Proteases are one of the most important and historically utilized classes of drug targets. To effectively interrogate this class of proteins, which encodes nearly 2% of the human proteome, it is necessary to develop effective and cost-efficient methods that report on their activity both in vitro and...

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Detalhes bibliográficos
Main Authors: Wu, Peng, Nicholls, Samantha B., Hardy, Jeanne A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617415/
https://ncbi.nlm.nih.gov/pubmed/23561537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.058
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