Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype

Expansions of the non-coding GGGGCC hexanucleotide repeat in the chromosome 9 open reading frame 72 (C9ORF72) gene were recently identified as the long sought-after cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) on chromosome 9p. In this study we aimed to determine wh...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Rutherford, Nicola J., Heckman, Michael G., DeJesus-Hernandez, Mariely, Baker, Matt C., Soto-Ortolaza, Alexandra I., Rayaprolu, Sruti, Stewart, Heather, Finger, Elizabeth, Volkening, Kathryn, Seeley, William W., Hatanpaa, Kimmo J., Lomen-Hoerth, Catherine, Kertesz, Andrew, Bigio, Eileen H., Lippa, Carol, Knopman, David S., Kretzschmar, Hans A., Neumann, Manuela, Caselli, Richard J., White, Charles L., Mackenzie, Ian R., Petersen, Ronald C., Strong, Michael J., Miller, Bruce L., Boeve, Bradley F., Uitti, Ryan J., Boylan, Kevin, Wszolek, Zbigniew K., Graff-Radford, Neill R., Dickson, Dennis W., Ross, Owen A., Rademakers, Rosa
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617405/
https://ncbi.nlm.nih.gov/pubmed/22840558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.07.005
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki