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The Benefits of Using Genetic Information to Design Prevention Trials

Clinical trials for preventative therapies are complex and costly endeavors focused on individuals likely to develop disease in a short time frame, randomizing them to treatment groups, and following them over time. In such trials, statistical power is governed by the rate of disease events in each...

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Main Authors: Hu, Youna, Li, Li, Ehm, Margaret G., Bing, Nan, Song, Kijoung, Nelson, Matthew R., Talmud, Philippa J., Hingorani, Aroon D., Kumari, Meena, Kivimäki, Mika, Xu, Chun-Fang, Waterworth, Dawn M., Whittaker, John C., Abecasis, Gonçalo R., Spino, Cathie, Kang, Hyun Min
格式: Artigo
語言:Inglês
出版: Elsevier 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617383/
https://ncbi.nlm.nih.gov/pubmed/23541341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.03.003
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