Diacylglycerol Acyltransferase-1 Localizes Hepatitis C Virus NS5A Protein to Lipid Droplets and Enhances NS5A Interaction with the Viral Capsid Core

The triglyceride-synthesizing enzyme acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) plays a critical role in hepatitis C virus (HCV) infection by recruiting the HCV capsid protein core onto the surface of cellular lipid droplets (LDs). Here we find a new interaction between the non-structural pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Camus, Gregory, Herker, Eva, Modi, Ankit A., Haas, Joel T., Ramage, Holly R., Farese, Robert V., Ott, Melanie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Microbiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617291/
https://ncbi.nlm.nih.gov/pubmed/23420847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434910
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