Extracellular Signal-regulated Kinase and Glycogen Synthase Kinase 3β Regulate Gephyrin Postsynaptic Aggregation and GABAergic Synaptic Function in a Calpain-dependent Mechanism

Molecular mechanisms of plasticity at GABAergic synapses are currently poorly understood. To identify signaling cascades that converge onto GABAergic postsynaptic density proteins, we performed MS analysis using gephyrin isolated from rat brain and identified multiple novel phosphorylation and acety...

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Hauptverfasser: Tyagarajan, Shiva K., Ghosh, Himanish, Yévenes, Gonzalo E., Imanishi, Susumu Y., Zeilhofer, Hanns Ulrich, Gerrits, Bertran, Fritschy, Jean-Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617267/
https://ncbi.nlm.nih.gov/pubmed/23408424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.442616
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