Combined TLR7/8 and TLR9 Ligands Potentiate the Activity of a Schistosoma japonicum DNA Vaccine

BACKGROUND: Toll-like receptor (TLR) ligands have been explored as vaccine adjuvants for tumor and virus immunotherapy, but few TLR ligands affecting schistosoma vaccines have been characterized. Previously, we developed a partially protective DNA vaccine encoding the 26-kDa glutathione S-transferas...

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Detalhes bibliográficos
Main Authors: Wang, Xuefeng, Dong, Liyang, Ni, Hongchang, Zhou, Sha, Xu, Zhipeng, Hoellwarth, Jason Shih, Chen, Xiaojun, Zhang, Rongbo, Chen, Qiaoyun, Liu, Feng, Wang, Jun, Su, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617091/
https://ncbi.nlm.nih.gov/pubmed/23593527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002164
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