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Sex and Age Modify Biochemical and Skeletal Manifestations of Chronic Hyperparathyroidism by Altering Target Organ Responses to Ca(2+) and PTH in Mice
We studied mice with or without heterozygous deletion of the Casr in the parathyroid gland (PTG) [(PTG)CaSR(+/−)] to delineate effects of age and sex on manifestations of hyperparathyroidism (HPT). In control mice, aging induced a left-shift in the Ca(2+)/parathyroid hormone (PTH) set-point accompan...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617088/ https://ncbi.nlm.nih.gov/pubmed/23239173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1846 |
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