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Evolutionary Capacitance and Control of Protein Stability in Protein-Protein Interaction Networks

In addition to their biological function, protein complexes reduce the exposure of the constituent proteins to the risk of undesired oligomerization by reducing the concentration of the free monomeric state. We interpret this reduced risk as a stabilization of the functional state of the protein. We...

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Detalhes bibliográficos
Main Authors: Dixit, Purushottam D., Maslov, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617028/
https://ncbi.nlm.nih.gov/pubmed/23592969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003023
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