Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells

Increased physiological levels of oxysterols are major risk factors for developing atherosclerosis and cardiovascular disease. Lipid-loaded macrophages, termed foam cells, are important during the early development of atherosclerotic plaques. To pursue the hypothesis that ligand-based modulation of...

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Main Authors: Feldmann, Radmila, Fischer, Cornelius, Kodelja, Vitam, Behrens, Sarah, Haas, Stefan, Vingron, Martin, Timmermann, Bernd, Geikowski, Anne, Sauer, Sascha
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616743/
https://ncbi.nlm.nih.gov/pubmed/23393188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt034
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