Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange

The MYST HAT Sas2 is part of the SAS-I complex that acetylates histone H4 lysine 16 (H4 K16Ac) and blocks the propagation of heterochromatin at the telomeres of Saccharomyces cerevisiae. In this study, we investigated Sas2-mediated H4 K16Ac on a genome-wide scale. Interestingly, H4 K16Ac loss in sas...

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Detalhes bibliográficos
Main Authors: Heise, Franziska, Chung, Ho-Ryun, Weber, Jan M., Xu, Zhenyu, Klein-Hitpass, Ludger, Steinmetz, Lars M., Vingron, Martin, Ehrenhofer-Murray, Ann E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245914/
https://ncbi.nlm.nih.gov/pubmed/21908408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr649
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