Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

A key step in proliferation of retroviruses is the conversion of their RNA genome to double-stranded DNA, a process catalysed by multifunctional reverse transcriptases (RTs). Dimeric and monomeric RTs have been described, the latter exemplified by the enzyme of Moloney murine leukaemia virus. Howeve...

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Detalhes bibliográficos
Main Authors: Nowak, Elżbieta, Potrzebowski, Wojciech, Konarev, Petr V., Rausch, Jason W., Bona, Marion K., Svergun, Dmitri I., Bujnicki, Janusz M., Le Grice, Stuart F. J., Nowotny, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616737/
https://ncbi.nlm.nih.gov/pubmed/23382176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt053
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