Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub

The current progress in the study of the spatial organization of interphase chromosomes became possible owing to the development of the chromosome conformation capture (3C) protocol. The crucial step of this protocol is the proximity ligation—preferential ligation of DNA fragments assumed to be join...

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Main Authors: Gavrilov, Alexey A., Gushchanskaya, Ekaterina S., Strelkova, Olga, Zhironkina, Oksana, Kireev, Igor I., Iarovaia, Olga V., Razin, Sergey V.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616722/
https://ncbi.nlm.nih.gov/pubmed/23396278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt067
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