Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes

Massive palindromes in the human Y chromosome harbor mirror-image gene pairs essential for spermatogenesis. During evolution, these gene pairs have been maintained by intrapalindrome, arm-to-arm recombination. The mechanism of intrapalindrome recombination and risk of harmful effects are unknown. We...

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Bibliografiske detaljer
Main Authors: Lange, Julian, Skaletsky, Helen, van Daalen, Saskia K.M., Embry, Stephanie L., Korver, Cindy M., Brown, Laura G., Oates, Robert D., Silber, Sherman, Repping, Sjoerd, Page, David C.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616640/
https://ncbi.nlm.nih.gov/pubmed/19737515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.042
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