Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population

Background. The nonnucleoside reverse transcriptase inhibitor nevirapine is the cornerstone of treatment for human immunodeficiency virus (HIV) in many sub-Saharan African countries. However, nevirapine is associated with a 6%–10% risk of developing a hypersensitivity reaction, with different phenot...

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Detalhes bibliográficos
Main Authors: Carr, Daniel F., Chaponda, Mas, Jorgensen, Andrea L., Castro, Elena Cornejo, van Oosterhout, Joep J., Khoo, Saye H., Lalloo, David G., Heyderman, Robert S., Alfirevic, Ana, Pirmohamed, Munir
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
HIV/AIDS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616517/
https://ncbi.nlm.nih.gov/pubmed/23362284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cit021
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