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Statin-dependent activation of protein kinase C delta (PKCδ) in APL cells and induction of leukemic cell differentiation

Statins are HMG-CoA reductase inhibitors, which block the conversion of HMG-CoA to mevalonate and have potent cholesterol lowering properties. Beyond their importance in generation of lipid lowering effects, the regulatory effects of statins on the mevalonate pathway have significant impact on multi...

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Detalhes bibliográficos
Main Authors: Sassano, Antonella, Altman, Jessica K., Gordon, Leo I., Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616499/
https://ncbi.nlm.nih.gov/pubmed/22356114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.668287
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