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Canonical and Atypical E2Fs Regulate the Mammalian Endocycle
The endocycle is a variant cell cycle consisting of successive DNA synthesis and Gap phases that yield highly polyploid cells. Although essential for metazoan development, relatively little is known about its control or physiologic role in mammals. Using novel lineage-specific cre mice we identified...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616487/ https://ncbi.nlm.nih.gov/pubmed/23064266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2595 |
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