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A signal processing approach for enriched region detection in RNA polymerase II ChIP-seq data

BACKGROUND: RNA polymerase II (PolII) is essential in gene transcription and ChIP-seq experiments have been used to study PolII binding patterns over the entire genome. However, since PolII enriched regions in the genome can be very long, existing peak finding algorithms for ChIP-seq data are not ad...

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Main Authors: Han, Zhi, Tian, Lu, Pécot, Thierry, Huang, Tim, Machiraju, Raghu, Huang, Kun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375632/
https://ncbi.nlm.nih.gov/pubmed/22536865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S2-S2
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