BAFF Receptor mAb Treatment Ameliorates Development and Progression of Atherosclerosis in Hyperlipidemic ApoE(−/−) Mice

AIMS: Option to attenuate atherosclerosis by depleting B2 cells is currently limited to anti-CD20 antibodies which deplete all B-cell subtypes. In the present study we evaluated the capacity of a monoclonal antibody to B cell activating factor-receptor (BAFFR) to selectively deplete atherogenic B2 c...

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Autori principali: Kyaw, Tin, Cui, Peng, Tay, Christopher, Kanellakis, Peter, Hosseini, Hamid, Liu, Edgar, Rolink, Antonius G., Tipping, Peter, Bobik, Alex, Toh, Ban-Hock
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616162/
https://ncbi.nlm.nih.gov/pubmed/23560095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060430
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