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Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk Prediction

BACKGROUND: Genome-wide association studies (GWAS) have identified multiple SNPs associated with prostate cancer (PrCa). Population isolates may have different sets of risk alleles for PrCa constituting unique population and individual risk profiles. METHODS: To test this hypothesis, associations be...

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Hlavní autoři: Agalliu, Ilir, Wang, Zhaoming, Wang, Tao, Dunn, Anne, Parikh, Hemang, Myers, Timothy, Burk, Robert D., Amundadottir, Laufey
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616024/
https://ncbi.nlm.nih.gov/pubmed/23573233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060083
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