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How much are we missing in SNP-by-SNP analyses of GWAS?

Genome-wide association studies have discovered common genetic variants associated with susceptibility for several complex diseases; but they have been unfruitful for many others. Typically analysis is done by “agnostically” considering one single nucleotide polymorphism (SNP) at a time, controlling...

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Detalhes bibliográficos
Publicado no:Epidemiology
Main Authors: Shi, Min, Weinberg, Clarice R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779601/
https://ncbi.nlm.nih.gov/pubmed/21878815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0b013e31822ffbe7
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