MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines

The resistance of hypoxic cells to radiotherapy and chemotherapy is a major problem in the treatment of cancer. Recently, an additional mode of hypoxia-inducible factor (HIF)-dependent transcriptional regulation, involving modulation of a specific set of micro RNAs (miRNAs), including miR-210, has e...

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Bibliographic Details
Main Authors: Grosso, S, Doyen, J, Parks, S K, Bertero, T, Paye, A, Cardinaud, B, Gounon, P, Lacas-Gervais, S, Noël, A, Pouysségur, J, Barbry, P, Mazure, N M, Mari, B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615727/
https://ncbi.nlm.nih.gov/pubmed/23492775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.71
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