Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform

Anti-vector immunity mitigates immune responses induced by recombinant adenovirus vector vaccines, limiting their prime-boost capabilities. We have developed a novel gene delivery and expression platform (Ad5 [E1-, E2b-]) that induces immune responses despite preexisting and/or developed concomitant...

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Detalhes bibliográficos
Main Authors: Gabitzsch, Elizabeth S., Balint-Junior, Joseph P., Xu, Younong, Balcaitis, Stephanie, Sanders-Beer, Brigitte, Karl, Julie, Weinhold, Kent J., Paessler, Slobodan, Jones, Frank R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615555/
https://ncbi.nlm.nih.gov/pubmed/23041546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.09.058
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