Plasminogen Activator Inhibitor-1 Mitigates Brain Injury in a Rat Model of Infection-Sensitized Neonatal Hypoxia–Ischemia

Intrauterine infection exacerbates neonatal hypoxic–ischemic (HI) brain injury and impairs the development of cerebral cortex. Here we used low-dose lipopolysaccharide (LPS) pre-exposure followed by unilateral cerebral HI insult in 7-day-old rats to study the pathogenic mechanisms. We found that LPS...

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Detalhes bibliográficos
Main Authors: Yang, Dianer, Sun, Yu-Yo, Nemkul, Niza, Baumann, Jessica M., Shereen, Ahmed, Dunn, R. Scott, Wills-Karp, Marsha, Lawrence, Daniel A., Lindquist, Diana M., Kuan, Chia-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615353/
https://ncbi.nlm.nih.gov/pubmed/22556277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhs115
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