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Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene.

The promoter of the gene encoding a cytoplasmic guanylate-binding protein (GBP) contains two overlapping elements: the interferon stimulation response element (ISRE), which mediates alpha interferon (IFN-alpha)-dependent transcription, and the IFN-gamma activation site (GAS), which is required for I...

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Библиографические подробности
Главные авторы: Decker, T, Lew, D J, Darnell, J E
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC361534/
https://ncbi.nlm.nih.gov/pubmed/1833631
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