Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

Osteoarthritis (OA) is the most prevalent form of arthritis and accounts for substantial morbidity and disability, particularly in the elderly. It is characterized by changes in joint structure including degeneration of the articular cartilage and its etiology is multifactorial with a strong postula...

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Main Authors: Evangelou, Evangelos, Valdes, Ana M., Kerkhof, Hanneke J.M, Styrkarsdottir, Unnur, Zhu, YanYan, Meulenbelt, Ingrid, Lories, Rik J., Karassa, Fotini B., Tylzanowski, Przemko, Bos, Steffan D., Akune, Toru, Arden, Nigel K., Carr, Andrew, Chapman, Kay, Cupples, L. Adrienne, Dai, Jin, Deloukas, Panos, Doherty, Michael, Doherty, Sally, Engstrom, Gunnar, Gonzalez, Antonio, Halldorsson, Bjarni V., Hammond, Christina L., Hart, Deborah J., Helgadottir, Hafdis, Hofman, Albert, Ikegawa, Shiro, Ingvarsson, Thorvaldur, Jiang, Qing, Jonsson, Helgi, Kaprio, Jaakko, Kawaguchi, Hiroshi, Kisand, Kalle, Kloppenburg, Margreet, Kujala, Urho M., Lohmander, L. Stefan, Loughlin, John, Luyten, Frank P., Mabuchi, Akihiko, McCaskie, Andrew, Nakajima, Masahiro, Nilsson, Peter M., Nishida, Nao, Ollier, William E.R., Panoutsopoulou, Kalliope, van de Putte, Tom, Ralston, Stuart H., Rivadeneira, Fernado, Saarela, Janna, Schulte-Merker, Stefan, Slagboom, P. Eline, Sudo, Akihiro, Tamm, Agu, Tamm, Ann, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tsezou, Aspasia, Wallis, Gillian A., Wilkinson, J. Mark, Yoshimura, Noriko, Zeggini, Eleftheria, Zhai, Guangju, Zhang, Feng, Jonsdottir, Ingileif, Uitterlinden, Andre G., Felson, David T, van Meurs, Joyce B., Stefansson, Kari, Ioannidis, John P.A., Spector, Timothy D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615180/
https://ncbi.nlm.nih.gov/pubmed/21068099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2010.132787
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