Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations

Osteoarthritis (OA) is the most common form of arthritis and a major cause of disability. This study evaluates the association in Caucasian populations of two single nucleotide polymorphisms (SNPs) mapping to the Human Leukocyte Antigen (HLA) region and deriving from a genome wide association scan (...

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Detalhes bibliográficos
Main Authors: Valdes, Ana M., Styrkarsdottir, Unnur, Doherty, Michael, Morris, David L., Mangino, Massimo, Tamm, Agu, Doherty, Sally A., Kisand, Kalle, Kerna, Irina, Tamm, Ann, Wheeler, Margaret, Maciewicz, Rose A., Zhang, Weiya, Muir, Kenneth R., Dennison, Elaine M., Hart, Deborah J., Metrustry, Sarah, Jonsdottir, Ingileif, Jonsson, Gudbjorn F., Jonsson, Helgi, Ingvarsson, Thorvaldur, Cooper, Cyrus, Vyse, Timothy J., Spector, Tim D., Stefansson, Kari, Arden, Nigel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154440/
https://ncbi.nlm.nih.gov/pubmed/21853121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023371
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