Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations

Osteoarthritis (OA) is the most common form of arthritis and a major cause of disability. This study evaluates the association in Caucasian populations of two single nucleotide polymorphisms (SNPs) mapping to the Human Leukocyte Antigen (HLA) region and deriving from a genome wide association scan (...

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Hlavní autoři: Valdes, Ana M., Styrkarsdottir, Unnur, Doherty, Michael, Morris, David L., Mangino, Massimo, Tamm, Agu, Doherty, Sally A., Kisand, Kalle, Kerna, Irina, Tamm, Ann, Wheeler, Margaret, Maciewicz, Rose A., Zhang, Weiya, Muir, Kenneth R., Dennison, Elaine M., Hart, Deborah J., Metrustry, Sarah, Jonsdottir, Ingileif, Jonsson, Gudbjorn F., Jonsson, Helgi, Ingvarsson, Thorvaldur, Cooper, Cyrus, Vyse, Timothy J., Spector, Tim D., Stefansson, Kari, Arden, Nigel K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154440/
https://ncbi.nlm.nih.gov/pubmed/21853121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023371
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