Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity

BACKGROUND: Most personalized cancer care strategies involving DNA sequencing are highly reliant on acquiring sufficient fresh or frozen tissue. It has been challenging to comprehensively evaluate the genome of advanced prostate cancer (PCa) because of limited access to metastatic tissue. OBJECTIVE:...

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Autors principals: Beltran, Himisha, Yelensky, Roman, Frampton, Garrett M., Park, Kyung, Downing, Sean R., MacDonald, Theresa Y., Jarosz, Mirna, Lipson, Doron, Tagawa, Scott T., Nanus, David M., Stephens, Philip J., Mosquera, Juan Miguel, Cronin, Maureen T., Rubin, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615043/
https://ncbi.nlm.nih.gov/pubmed/22981675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.08.053
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