Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism.
Stimulation of quiescent cultured fibroblasts with a variety of growth-promoting factors induces release of diacylglycerol (DG) and subsequent activation of protein kinase C (pkC), but the role of pkC in the induction of DNA synthesis and cell proliferation remains unclear. We have investigated the...
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| Опубліковано в:: | Cell Regul |
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| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Cell Biology
1990
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2129223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.4.379 |
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