Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of Rat-1 fibroblasts through a protein kinase C-dependent mechanism.

Stimulation of quiescent cultured fibroblasts with a variety of growth-promoting factors induces release of diacylglycerol (DG) and subsequent activation of protein kinase C (pkC), but the role of pkC in the induction of DNA synthesis and cell proliferation remains unclear. We have investigated the...

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Detalhes bibliográficos

Publicado no:	Cell Regul
Principais autores:	Muldoon, L L, Pribnow, D, Rodland, K D, Magun, B E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2129223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.4.379
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