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The Calpain/Calpastatin System Has Opposing Roles in Growth and Metastatic Dissemination of Melanoma
Conventional calpains are ubiquitous cysteine proteases whose activity is promoted by calcium signaling and specifically limited by calpastatin. Calpain expression has been shown to be increased in human malignant cells, but the contribution of the calpain/calpastatin system in tumorigenesis remains...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3614974/ https://ncbi.nlm.nih.gov/pubmed/23565252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060469 |
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