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Impact of E1 and Cre on Adenovirus Vector Amplification: Developing MDCK CAV-2-E1 and E1-Cre Transcomplementing Cell Lines

Adenovirus vectors have been extensively studied through the manipulation of viral genome. However, little attention is being paid to their producer cell-lines; cells are selected according to virus yields, neglecting the expression profile of transcomplementing gene products underlying cell perform...

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Main Authors: Fernandes, Paulo, Santiago, Virgínia M., Rodrigues, Ana F., Tomás, Hélio, Kremer, Eric J., Alves, Paula M., Coroadinha, Ana S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614972/
https://ncbi.nlm.nih.gov/pubmed/23565229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060342
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