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The Gating Mechanism of the Human Aquaporin 5 Revealed by Molecular Dynamics Simulations

Aquaporins are protein channels located across the cell membrane with the role of conducting water or other small sugar alcohol molecules (aquaglyceroporins). The high-resolution X-ray structure of the human aquaporin 5 (HsAQP5) shows that HsAQP5, as all the other known aquaporins, exhibits tetramer...

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Detalles Bibliográficos
Main Authors: Janosi, Lorant, Ceccarelli, Matteo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614956/
https://ncbi.nlm.nih.gov/pubmed/23565173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059897
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