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The gating mechanism of the bacterial mechanosensitive channel MscL revealed by molecular dynamics simulations: From tension sensing to channel opening

One of the ultimate goals of the study on mechanosensitive (MS) channels is to understand the biophysical mechanisms of how the MS channel protein senses forces and how the sensed force induces channel gating. The bacterial MS channel MscL is an ideal subject to reach this goal owing to its resolved...

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Detalhes bibliográficos
Main Authors: Sawada, Yasuyuki, Murase, Masaki, Sokabe, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508910/
https://ncbi.nlm.nih.gov/pubmed/23146938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21895
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