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The gating mechanism of the bacterial mechanosensitive channel MscL revealed by molecular dynamics simulations: From tension sensing to channel opening

One of the ultimate goals of the study on mechanosensitive (MS) channels is to understand the biophysical mechanisms of how the MS channel protein senses forces and how the sensed force induces channel gating. The bacterial MS channel MscL is an ideal subject to reach this goal owing to its resolved...

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Autori principali: Sawada, Yasuyuki, Murase, Masaki, Sokabe, Masahiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508910/
https://ncbi.nlm.nih.gov/pubmed/23146938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21895
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