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axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

Using a sensitive transfection-tumorigenicity assay, we have isolated a novel transforming gene from the DNA of two patients with chronic myelogenous leukemia. Sequence analysis indicates that the product of this gene, axl, is a receptor tyrosine kinase. Overexpression of axl cDNA in NIH 3T3 cells i...

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Main Authors: O'Bryan, J P, Frye, R A, Cogswell, P C, Neubauer, A, Kitch, B, Prokop, C, Espinosa, R, Le Beau, M M, Earp, H S, Liu, E T
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC361494/
https://ncbi.nlm.nih.gov/pubmed/1656220
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