Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

BACKGROUND: High invasion and metastasis are the primary factors causing poor prognosis of patients with hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying these biological behaviors have not been completely elucidated. In this study, we investigate the molecular mechanism...

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Detalhes bibliográficos
Main Authors: Zhang, Lin, Huang, Gang, Li, Xiaowu, Zhang, Yujun, Jiang, Yan, Shen, Junjie, Liu, Jia, Wang, Qingliang, Zhu, Jin, Feng, Xiaobin, Dong, Jiahong, Qian, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614870/
https://ncbi.nlm.nih.gov/pubmed/23496980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-108
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