Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

BACKGROUND: High invasion and metastasis are the primary factors causing poor prognosis of patients with hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying these biological behaviors have not been completely elucidated. In this study, we investigate the molecular mechanism...

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Autors principals: Zhang, Lin, Huang, Gang, Li, Xiaowu, Zhang, Yujun, Jiang, Yan, Shen, Junjie, Liu, Jia, Wang, Qingliang, Zhu, Jin, Feng, Xiaobin, Dong, Jiahong, Qian, Cheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614870/
https://ncbi.nlm.nih.gov/pubmed/23496980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-108
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