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Pamidronate Alters the Growth Plate in the Oim Mouse Model for Osteogenesis Imperfecta

Bisphosphonates alleviate bone pain and fractures associated with osteogenesis imperfecta (OI). Using the oim mouse model to simulate variations in OI severity, the effect of pamidronate on bone growth was assessed. Homozygous (oim/oim) and heterozygous (oim/wt) mice from 4 to 12 weeks of age were g...

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Autors principals: Evans, K. D., Sheppard, L. E., Rao, S. H., Martin, R. B., Oberbauer, A. M.
Format: Artigo
Idioma:Inglês
Publicat: Master Publishing Group 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614807/
https://ncbi.nlm.nih.gov/pubmed/23675157
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