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The Molecular Underpinnings of Centromere Identity and Maintenance
Centromeres direct faithful chromosome inheritance at cell division but are not defined by a conserved DNA sequence. Instead, a specialized form of chromatin containing the histone H3 variant, CENP-A, epigenetically specifies centromere location. We discuss current models where CENP-A serves as the...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3614489/ https://ncbi.nlm.nih.gov/pubmed/22410197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2012.01.003 |
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