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Catalytic Asymmetric Synthesis of Highly Substituted Pyrrolizidines

A catalytic asymmetric double (1,3)-dipolar cycloaddition reaction has been developed. Using a chiral silver catalyst, enantioenriched pyrrolizidines can be prepared in one flask from inexpensive, commercially available starting materials. The pyrrolizidine products contain a variety of substitution...

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Autors principals: Lim, Andrew D., Codelli, Julian A., Reisman, Sarah E.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614418/
https://ncbi.nlm.nih.gov/pubmed/23565328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC21617E
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