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Altered transcriptional activity of c-fos promoter plasmids in v-raf-transformed NIH 3T3 cells.

In cells transformed by v-raf, an oncogenic counterpart of the serine/threonine kinase Raf-1, regulatory elements of the c-fos promoter were active under conditions of cell growth or stimulation for which they were inactive in untransformed control cells. This suggests that v-raf transforms by dereg...

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Detalhes bibliográficos
Main Authors: Siegfried, Z, Ziff, E B
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361409/
https://ncbi.nlm.nih.gov/pubmed/2122238
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