Dysfunction of Collagen Synthesis and Secretion in Chondrocytes Induced by Wisp3 Mutation

Wisp3 gene mutation was shown to cause spondyloepiphyseal dysplasia tarda with progressive arthropathy (SRDT-PA), but the underlying mechanism is not clear. To clarify this mechanism, we constructed the wild and mutated Wisp3 expression vectors and transfected into human chondrocytes lines C-20/A4;...

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Detalhes bibliográficos
Main Authors: Wang, Min, Man, Xiao-Fei, Liu, Ya-Qing, Liao, Er-Yuan, Shen, Zhi-Feng, Luo, Xiang-Hang, Guo, Li-Juan, Wu, Xian-Ping, Zhou, Hou-De
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614060/
https://ncbi.nlm.nih.gov/pubmed/23573089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/679763
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