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IL-6 polymorphisms: a useful genetic tool for inflammation research?

In 1998, we described a novel polymorphism in the promoter (G>C, rs1800795) of the IL-6 (IL6) gene. The common allele, G, exhibited higher transcriptional activity in gene reporter assays and was associated with higher serum IL-6 levels in a small cohort of healthy subjects. We explored the ethni...

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Detalhes bibliográficos
Main Authors: Woo, Patricia, Humphries, Steve E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613933/
https://ncbi.nlm.nih.gov/pubmed/23543063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67221
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