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IL-6 polymorphisms: a useful genetic tool for inflammation research?
In 1998, we described a novel polymorphism in the promoter (G>C, rs1800795) of the IL-6 (IL6) gene. The common allele, G, exhibited higher transcriptional activity in gene reporter assays and was associated with higher serum IL-6 levels in a small cohort of healthy subjects. We explored the ethni...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613933/ https://ncbi.nlm.nih.gov/pubmed/23543063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67221 |
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