Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca(2+)/calmodulin signaling

TNF-related apoptosis-inducing ligand (TRAIL) is a promising cytokine for killing tumor cells. However, a number of studies have demonstrated that different cancer cells resist TRAIL treatment and, moreover, TRAIL can promote invasion and metastasis in resistant cells. Here we report that TRAIL rapi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kaminskyy, V O, Surova, O V, Piskunova, T, Zborovskaya, I B, Tchevkina, E M, Andera, L, Zhivotovsky, B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613829/
https://ncbi.nlm.nih.gov/pubmed/23470529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.51
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk